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Table 9 Empirical occurrence rate of the identified sequon in PTMs of proteins

From: Ridge regression estimated linear probability model predictions of O-glycosylation in proteins with structural and sequence data

Sequona (viewed from S/T/Y/H as “center”)

% of Sequences in the collected data that are:

O-GlcNAc glycosylated

O-GalNAc glycosylated

Phosphorylated

N – P – S/T

0.24%

0.43%

0.145%

N – ~P – S/T

1.22% (0.5%, 2.8%) b

0.77% (0.5%, 1.2%) b

2.858% (2.8%, 2.9%) b

~N – X – S/T

98.54% (96.9%, 99.3%) b

98.80% (98.2%, 99.2%) b

80.453%

~N – X – Y

Not applicable

Not applicable

15.748%

~N – X – H

Not applicable

Not applicable

0.006%

~N – X – S/T/Y/H

Not applicable

Not applicable

96.2% (96.1%, 96.3%) b

W – S/T – W

0%

0%

0.0066% (0.004%, 0.011%) b

~W – S/T – ~W

100%

98.94% (98.4%, 99.3%) b

82.3133%

~W – S/T – W

0%

0.58% (0.33%, 1.0%) b

0.6422%

W – S/T – ~W

0%

0.48% (0.26%, 0.88%) b

0.4930%

W – Y/H – W

Not applicable

Not applicable

0.0004%

~W – Y/H – ~W

Not applicable

Not applicable

16.2587%

W – Y/H – ~W

Not applicable

Not applicable

0.1365%

~W – Y/H – W

Not applicable

Not applicable

0.1462%

Sequence count

411

2,079

227,810

  1. aX denotes any amino acid. b 95% confidence interval [44]