Fig. 7From: The binding affinity of PTPN13’s tandem PDZ2/3 domain is allosterically modulatedSchematic functional model of the APC-bound PDZ1/2/3 domain triplet from PTPN13. Note, the proximate domains PDZ1 and PDZ3 interact with a mutually exclusive surface patch on PDZ2 located opposite to the canonical ligand binding site of PDZ domainsBack to article page