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Table 3 Protein quality characterization

From: CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches

Protein name Isotype Monomer % by SEC Endotoxin levela Mass Spec. Identityb
Heavy chain Light chain
FAB518 hCg1_z,non-a Kappa 100 < 0.1 EU/mg Consistent
FAB516 hCg1_z,non-a Kappa 100 < 0.1 EU/mg Consistent
CP 870,893 hCg1_z,non-a Kappa 99 < 0.1 EU/mg Consistent
ABBV-323 hCg1_z,non-a Kappa 100 < 0.4 EU/mg Consistent
  1. aEndotoxin levels assessed by PTS EndoSafe LAL
  2. bExpected (theoretical) molecular weight (MW) is consistent with measured MW by Mass Spec