Skip to main content

Advertisement

Fig. 4 | BMC Molecular and Cell Biology

Fig. 4

From: In silico prediction of structural changes in human papillomavirus type 16 (HPV16) E6 oncoprotein and its variants

Fig. 4

Amino acids from the non-synonymous sites among the E6 reference and its variants. a Two different amino acids at position 14 (Q14) in the sequence alignment between the reference E6 oncoprotein and AAa and AAc variants; b Two different amino acids at position 25 (D25) between the reference E6 oncoprotein and alternative E6-A-176/G350 are shown; c Amino acid at position 27 (I27) of the E6 oncoprotein reference differs in the variant AAc by R27; d The amino acid at position 29 (E29) differs in the variant E6-C188/G350; e shows the amino acid at position 78 (H78) that differs in the AAa and AAc variants; f shows the amino acid at position 83 (L83) which is mutated in all variants. The same colors are used across panels for different amino acids from the same variant. Different colors are used as follow: E6 reference oncoprotein (blue), E6-G350 (yellow), E6-A176/G350 (green), E6-C188/G350 (cyan), E6 AAa (pink) and E6 AAc (orange). The silver spheres indicate zinc molecules. The orientation of the amino acids is defined by the axes shown (X: red, Y: green; Z: blue)

Back to article page