Fig. 6
Multiple regression analysis of relationships between protein pI, intra-organelle pH and membrane charge. The variables X1 and X2 in the linear (a) and polynomial (b) regressions, indicated above the graphs, refer to organelle pH and membrane charge, correspondingly. Spearman’s coefficients and their p-values were determined for correlations between the mean pIs of the localization-specific distributions, as presented in Fig. 2, and the pI values calculated with the use of the indicated regression functions