From: Localization-specific distributions of protein pI in human proteome are governed by local pH and membrane charge
Compartment
pH (2009)
pH (2015)
Charge, %
Cytoplasm
7.3
7.2
0.0
Nucleus
7.7
17.4
E.R.
7.1
MX
7.5
8.0
10.0
Golgi
6.6
6.0–6.7
Peroxisome
8.2
7.0
2.0
Lysosome
4.8
4.7
Membrane
–
8.5