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Fig. 2 | BMC Molecular and Cell Biology

Fig. 2

From: LncRNA MEG3 influences the proliferation and apoptosis of psoriasis epidermal cells by targeting miR-21/caspase-8

Fig. 2

LncRNA MEG3 inhibited proliferation and promotes apoptosis of Act-HaCaT and Act-HHEK. a Transfection efficiency of sh-MEG3 and pcDNA-MEG3 in cells was measured by qRT-PCR; b Influence of MEG3 expression on the proliferation of Act-HaCaT and Act-HHEK was measured by MTT assay; c Influence of MEG3 expression on the proliferation of Act-HaCaT and Act-HHEK was measured by clone formation assay; d Overexpression of MEG3 promoted the apoptosis of Act-HaCaT and Act-HHEK; e Knockdown of MEG3 inhibited the apoptosis of Act-HaCaT and Act-HHEK. f caspase-8, Bax, and Bcl-2 protein levels after transfecting vector, pcDNA-MEG3, sh-NC, and sh-MEG4, respectively. All the results were shown as mean ± SD (n = 3), and the experiments were repeated three times

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