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Fig. 4 | BMC Molecular and Cell Biology

Fig. 4

From: LncRNA MEG3 influences the proliferation and apoptosis of psoriasis epidermal cells by targeting miR-21/caspase-8

Fig. 4

LncRNA MEG3 affected the proliferation and apoptosis of Act-HaCaT and Act-HHEK by regulating miR-21. a Cell proliferation of Act-HaCaT and Act-HHEK was measured by MTT assay after transfection with vector+miR- NC, pcDNA-MEG3 + miR- NC, and pcDNA-MEG3 + miR-21 minmic, respectively; b Cell proliferation of Act-HaCaT and Act-HHEK was measured by clone formation assay after transfection with vector+miR- NC, pcDNA-MEG3 + miR- NC, and pcDNA-MEG3 + miR-21 minmic, respectively; c Influence of co-transfection using pcDNA-MEG3 + miR- NC and miR-21inhibitor on apoptosis of Act-HaCaT and Act-HHEK; d Influence of transfection with vector+miR-NC, pcDNA-MEG3 + miR- NC and pcDNA-MEG3+ miR-21 mimic on the expression of caspase-8, Bax, and Bcl-2, respectively. All the results were shown as mean ± SD (n = 3), and the experiments were repeated three times

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