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Fig. 5 | BMC Molecular and Cell Biology

Fig. 5

From: LncRNA MEG3 influences the proliferation and apoptosis of psoriasis epidermal cells by targeting miR-21/caspase-8

Fig. 5

miR-21 inhibited the expression of caspase-8 in Act-HaCaT and Act-HHEK. a Prediction of the binding site between miR-21 and caspase-8; b Transfection with miR-21 mimic and caspase-8 WT decreased the relative luciferase activity (miR-21/miR-NC); c Transfection with miR-21 mimic significantly decreased the expression of caspase-8; d The expression of caspase-8 measured by western blotting after transfection with miR-21 inhibitor, miR-21 mimic, caspase-8 mRNA, and caspase-8 shRNA, respectively. All the results were shown as mean ± SD (n = 3), and the experiments were repeated three times

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