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Table 2 Effect of fibrin γ/γ’ on secretion of uPA and PAI 1 by HMEC-1. Results are expressed as mean ± standard error (SE). Experiments were performed each time in triplicate in three independent experiments

From: Fibrin γ/γ' influences the secretion of fibrinolytic components and clot structure

  uPA PAI 1
SN CL SN CL
Basal 0.56 ± 0.09 0.40 ± 0.01 2569 ± 344 1055 ± 85
3% γ/γ’ 0.39 ± 0.13 1.73 ± 0.11**ξ 3398 ± 436 770 ± 74
30% γ/γ’ 1.06 ± 0.04* 3.21 ± 0.03** 5976 ± 918* 1845 ± 201*
Thrombin 1.04 ± 0.09* 2.42 ± 0.48** 6464 ± 455* 1422 ± 229*
  1. SN: supernatant; CL: cell lysate (1000 cells/μL). uPA and PAI 1 concentrations are in ng/mL
  2. *p < 0.05 when compared to the basal condition and 3% fibrin γ/γ’
  3. **p < 0.05 when compared to the basal condition
  4. ξp < 0.05 when compared to 30% fibrin γ/γ’