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Table 2 Isolated antigen HER2 recognition in the ELISA test to assess the mAb folding with chains physical separation

From: Heavy chain dimers stabilized by disulfide bonds are required to promote in vitro assembly of trastuzumab

Molecule

In vivo folded LC

In vivo folded HC

Refolded trastuzumab

Isolated antigen HER2 recognition

ND

ND

54 ± 6 AU/μg