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Table 2 Isolated antigen HER2 recognition in the ELISA test to assess the mAb folding with chains physical separation

From: Heavy chain dimers stabilized by disulfide bonds are required to promote in vitro assembly of trastuzumab

MoleculeIn vivo folded LCIn vivo folded HCRefolded trastuzumab
Isolated antigen HER2 recognitionNDND54 ± 6 AU/μg