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Fig. 2 | BMC Molecular and Cell Biology

Fig. 2

From: PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth

Fig. 2

PGRMC1 phosphorylation status affects motility and invasion. a DM cells exhibit enhanced motility in a scratch assay. Representative results for the scratch assay after 36 h of cell migration. Cells in the boxed area of the scratched void area for each image were counted. b Scratch assay cell migration results. Box plots of cell migration into the scratch void box areas depicted in (A) for multiple replicates. n = 12 (MP), or 4 replicates each of sublines 1–3 for WT and TM (n = 3 × 4 = 12). The table shows the results of 1 way ANOVA with post-hoc Dunnet’s T3 p-values. Video files of cell migration are available in File S1. c DM cells exhibit reduced invasion in Geltrex invasion assay. Representative images of crystal-violet stained cells in the lower surface of the transwell insert. d Boxplots of invasion assay results from (C) for replicates, as produced by SPSS software. n = 30 (MP), or 10 replicates each of sublines 1–3 for WT and TM (n = 3 × 10 = 30). The table shows the Kruskal-Wallis p-values for pairwise comparisons

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