Fig. 4

Pathways enrichment suggests altered cell cycle control proteins. a Abundances of proteins detected as significantly differentially abundant in indicated Pathways Commons pathways by enrichment analysis (Accompanying paper [10]) at the adjP < 5% significance level. (b, c, e-g) Average reverse phase protein array (RPPA) normalized fluorescent intensity (NFI) from the indicated antibodies (see methods) is plotted from 6 replicate measurements. NFI is normalized to protein content. Significance levels are * p < 0.05, ** p < 0.01, *** p < 0.001. Conventions follow those of the accompanying paper [10]. d The ratio of average NFI of the anti-pRB antibody to that of the RB antibody