Fig. 3
Schematic drawing of an ADM. A line parallel to the y-axis at the i-th residue divides the map into two parts (a), and a line parallel to the x-axis at the i-th residue divides the map into two parts (b). The density of the plots in the trapezoidal part and the triangular parts are denoted by ρi and \( {\overset{\sim }{\rho}}_i. \) A hypothetical map with two compact areas near the diagonal is shown, along with the horizontal and vertical scanning plots. This map predicts the existence of two domains at the regions p–q and m–n. We define η as a measure of the compactness of the region, namely, η = \( \Delta {\rho}_m^h+\Delta {\rho}_p^v \) and η = \( \Delta {\rho}_n^h+\Delta {\rho}_q^v \)