Analyses of the folding sites of irregular β-trefoil fold proteins through sequence-based techniques and Gō-model simulations

Table 1 Thirty target proteins selected for this study

Superfamily	PDB ID	UniProt ID	Protein name (UniProtKB)	Sequence length
Cytokine	2K8R	P05230	Fibroblast growth factor 1	133
	1Q1U	P61328	Fibroblast growth factor 12	138
	2FDB_M	P55075	Fibroblast growth factor 8	147
	1QQK	Q02195	Fibroblast growth factor 7	129
	1J0S	Q14116	Interleukin-18	157
	6I1B	P01584	Interleukin-1 beta (Homo sapiens [Human])	153
	1MD6	Q9QYY1	Interleukin-36 receptor antagonist protein	154
	2KKI	P01583	Interleukin-1 alpha	151
	2WRY	O73909	Interleukin-1 beta (Gallus gallus [Chicken])	155
	2P39	Q9GZV9	Fibroblast growth factor 23	142
	2P23	O95750	Fibroblast growth factor 19	136
Ricin B-like lectins	2RST	O96048	29-kDa galactose-binding lectin	132
	1SR4_A	O06522	Cytolethal distending toxin subunit A	167
	1SR4_C	O06524	Cytolethal distending toxin subunit C	154
	1KNM	P26514	Endo-1,4-beta-xylanase A	129
	1DQG	Q61830	Macrophage mannose receptor 1	134
STI-like	3BX1_D	P07596	Alpha-amylase/subtilisin inhibitor	181
	1TIE	P09943	Trypsin inhibitor DE-3	166
	1R8N	P83667	Kunitz-type serine protease inhibitor DrTI	185
	1WBA	P15465	Albumin-1	171
	2GZB	P83051	Kunitz-type proteinase inhibitor BbCI	164
	3ZC8	D2YW43	Trypsin inhibitor	182
	3TC2	Q8S380	KTI-B protein	181
	1A8D^a	P04958	Tetanus toxin	205
	1EPW^a	P10844	Clostridium neurotoxin type B	211
	3BTA^a	P0DPI1	Botulinum neurotoxin serotype A	204
Actin-crosslinking proteins	1HCD	P13231	Hisactophilin-1	118
MIR domain	1T9F	O61793	Protein R12E2.13 (Caenorhabditis elegans)	176
MIR domain	3HSM	P11716	Ryanodine receptor 1	164
DNA-binding protein LAG-1 (CSL)	1TTU^a	Q8MXE7	CSL bound to DNA	161

ISSN: 2661-8850