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Table 1 Citrate synthase activity in mitochondrial and cytosolic preparations

From: Basic biochemical characterization of cytosolic enzymes in thymidine nucleotide synthesis in adult rat tissues: implications for tissue specific mitochondrial DNA depletion and deoxynucleoside-based therapy for TK2-deficiency

Citrate synthase activity (μmol/min/mg)

Tissue

Mitochondrial

Cytosolic

Cytosolic/mitochondrial

Liver

12.1 ± 0.5

0.70 ± 0.04

0.057

Heart

54.3 ± 1.3

5.02 ± 0.18

0.092

Brain

45.8 ± 3.4

3.13 ± 0.06

0.068

Kidney

28.3 ± 1.2

2.23 ± 0.09

0.078

Spleen

41.8 ± 1.0

2.03 ± 0.03

0.048

Lung

61.0 ± 1.7

3.50 ± 0.06

0.057

Skeletal muscle

31.0 ± 1.2

2.6 ± 0.18

0.083