Table 2 List of 13-Potential Antigenic Proteins associated with Type 2 Diabetes Mellitus
Tissue Name | Gene Symbol | Uniprot_ID | Protein Names | Subcellular Localization |
|---|---|---|---|---|
Blood Brain Barrier | RAC1 | RAC1_HUMAN | Ras-related C3 botulinum toxin substrate 1 (Rho family) | Extracellular |
Intestinal | MMP2 | MMP2_HUMAN | Matrix metallopeptidase 2 (Gelatinase A, 72 kDa gelatinase) | Extracellular |
Pancreatic | TLR3 | TLR3_HUMAN | Toll-like receptor 3 (CD antigen CD283) | Extracellular |
Pancreatic | ITGB1 | ITB1_HUMAN | Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) | Extracellular |
Pancreatic | LTF | TRFL_HUMAN | Lactotransferrin (Lactoferrin) (Growth-inhibiting protein 12) | Extracellular |
Pancreatic | IL32 | IL32_HUMAN | Interleukin-32 (IL-32) (Natural killer cells protein 4) (Tumor necrosis factor alpha-inducing factor) | Extracellular |
Muscles | LRP6 | LRP6_HUMAN | Low-density lipoprotein receptor-related protein 6 (LRP-6) | Plasma membrane |
Muscles | LEPR | LEPR_HUMAN | LEPR protein (Fragment) | Extracellular |
Muscles | TGFB1 | TGFB1_HUMAN | Transforming growth factor, beta 1 (Camurati-Engelmann disease) | Extracellular |
Muscles | IGF1 | IGF1_HUMAN | Insulin-like growth factor I (IGF-I) (Somatomedin-C) | Extracellular |
Muscles | HLA-DRA | DRA_HUMAN | HLA-DRA (MHC class II antigen) (major histocompatibility complex | Plasma Membrane |
Lymphocytic | ABCB1 | A1L471_HUMAN | ATP-binding cassette, (MDR/TAP), member 1 | Plasma Membrane |
Lymphocytic | TRPM7 | TRPM7_HUMAN | Transient receptor potential cation channel subfamily M member 7 | Plasma Membrane |