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Table 2 List of 13-Potential Antigenic Proteins associated with Type 2 Diabetes Mellitus

From: Polyvalent therapeutic vaccine for type 2 diabetes mellitus: Immunoinformatics approach to study co-stimulation of cytokines and GLUT1 receptors

Tissue Name Gene Symbol Uniprot_ID Protein Names Subcellular Localization
Blood Brain Barrier RAC1 RAC1_HUMAN Ras-related C3 botulinum toxin substrate 1 (Rho family) Extracellular
Intestinal MMP2 MMP2_HUMAN Matrix metallopeptidase 2 (Gelatinase A, 72 kDa gelatinase) Extracellular
Pancreatic TLR3 TLR3_HUMAN Toll-like receptor 3 (CD antigen CD283) Extracellular
Pancreatic ITGB1 ITB1_HUMAN Integrin beta-1 (Fibronectin receptor subunit beta) (Glycoprotein IIa) Extracellular
Pancreatic LTF TRFL_HUMAN Lactotransferrin (Lactoferrin) (Growth-inhibiting protein 12) Extracellular
Pancreatic IL32 IL32_HUMAN Interleukin-32 (IL-32) (Natural killer cells protein 4) (Tumor necrosis factor alpha-inducing factor) Extracellular
Muscles LRP6 LRP6_HUMAN Low-density lipoprotein receptor-related protein 6 (LRP-6) Plasma membrane
Muscles LEPR LEPR_HUMAN LEPR protein (Fragment) Extracellular
Muscles TGFB1 TGFB1_HUMAN Transforming growth factor, beta 1 (Camurati-Engelmann disease) Extracellular
Muscles IGF1 IGF1_HUMAN Insulin-like growth factor I (IGF-I) (Somatomedin-C) Extracellular
Muscles HLA-DRA DRA_HUMAN HLA-DRA (MHC class II antigen) (major histocompatibility complex Plasma Membrane
Lymphocytic ABCB1 A1L471_HUMAN ATP-binding cassette, (MDR/TAP), member 1 Plasma Membrane
Lymphocytic TRPM7 TRPM7_HUMAN Transient receptor potential cation channel subfamily M member 7 Plasma Membrane