Table 1 List of up- and down-regulated gene sets

Up-regulated Gene Sets Name

Description

Count.

p-value

E2F targets

Genes encoding cell cycle related targets of E2F transcription factors.

24

6.09E-23

G2/M checkpoint

Genes involved in the G2/M checkpoint, as in progression through the cell division cycle.

24

6.09E-23

Mitotic spindle

Genes important for mitotic spindle assembly.

13

1.23E-09

MYC targets V1

A subgroup of genes regulated by MYC – version1 (V1).

13

1.23E-09

Down-regulated Gene Sets Name

Description

Count.

p-value

Xenobiotic metabolism

Genes encoding proteins involved in processing of drugs and other xenobiotics.

5

8.56E-04

Fatty acid metabolism

Genes encoding proteins involved in metabolism of fatty acids.

4

2.72E-03