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Fig. 3 | BMC Molecular and Cell Biology

Fig. 3

From: Exosomal miR-200c-3p negatively regulates the migration and invasion of lipopolysaccharide (LPS)-stimulated colorectal cancer (CRC)

Fig. 3

Selected miRNA expressions in gastro-intestinal cancer patients. a Heatmap of the selected top 15 differentially expressed miRNAs in control and LPS treated HCT-116-secreted exosomes; b Heatmap of selected top 15 differentially expressed miRNAs in colon cancer, gastric cancer and colorectal cancer. c miR-200c expression in CRC tissues and corresponding normal-appearing tissues from ten patients (n = 10). Data are acquired from GEO database (GSE126093). T-test was performed. * p < 0.05; d miR-200c expression in the serum exosome of CRC patients at stage 1 (n = 20), stage 2(n = 20), stage 3a(n = 20), stage 3b (n = 16) and stage 4 (n = 12). Healthy individuals (n = 11) were used as control (HC). FC: fold change. Data are acquired from GEO database (GSE39833). One-way ANOVA was performed. * p < 0.05; ** p < 0.01

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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