From: Glutantβase: a database for improving the rational design of glucose-tolerant β-glucosidases
Product (glucose) | ||||||
---|---|---|---|---|---|---|
Mutation | Affinity score (wild; 1–3) | Affinity score (mutant; 1–3) | Variation (ΔAS) | ΔAS expected | p-value | status |
A404V | −5.2930 | − 5.2988 | −0.0059 | ΔAS > 0 | 1 | X |
E96K | −5.3079 | −5.3083 | −0.0004 | ΔAS > 0 | 0.7174 | X |
H184F | −5.2912 | −5.2567 | 0.0345 | ΔAS > 0 | < 2.2e-16 | ✓ |
H228T | −5.3664 | −5.3149 | 0.0515 | ΔAS > 0 | < 2.2e-16 | ✓ |
L441F | −5.2366 | −5.2561 | −0.0195 | ΔAS > 0 | 1 | X |
V174C | −5.3045 | −5.3077 | −0.0032 | ΔAS > 0 | 0.9979 | X |