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Table 3 Docking results and hypothesis test for each protein wild and mutant docked to glucose (affinity score average for poses 1–3). For affinity scores, lower values represent more affinity. Affinity score variation (ΔAS)

From: Glutantβase: a database for improving the rational design of glucose-tolerant β-glucosidases

Product (glucose)
Mutation Affinity score (wild; 1–3) Affinity score (mutant; 1–3) Variation (ΔAS) ΔAS expected p-value status
A404V −5.2930 − 5.2988 −0.0059 ΔAS > 0 1 X
E96K −5.3079 −5.3083 −0.0004 ΔAS > 0 0.7174 X
H184F −5.2912 −5.2567 0.0345 ΔAS > 0 <  2.2e-16
H228T −5.3664 −5.3149 0.0515 ΔAS > 0 <  2.2e-16
L441F −5.2366 −5.2561 −0.0195 ΔAS > 0 1 X
V174C −5.3045 −5.3077 −0.0032 ΔAS > 0 0.9979 X