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Fig. 3 | BMC Molecular and Cell Biology

Fig. 3

From: A long non-coding RNA, HOTAIR, promotes cartilage degradation in osteoarthritis by inhibiting WIF-1 expression and activating Wnt pathway

Fig. 3

Western blot analysis of OA- and cartilage-related protein expression in SW1353 cells at 48 h after (a) siRNA-mediated knockdown of HOTAIR or (b) over-expression of HOTAIR by retrovirus infection. Protein expression levels of (c) MMP-13, (d) BMP-2, (e) ADAMTS5 and (f) SOX9 are measured by densitometry analysis. The HOTAIR knockdown and over-expression groups are expressed as a fold difference from their respective controls *P < 0.05

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