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Fig. 3 | BMC Molecular and Cell Biology

Fig. 3

From: An Endostatin-lentivirus (ES-LV)-EPC gene therapy agent for suppression of neovascularization in oxygen-induced retinopathy rat model

Fig. 3

Fundus fluorescein angiography representative photos. a A capillary non-perfusion zone and neovascularization leakage were observed in the experimental group but not in the control group. Fluorescein leakage in the neovascular area (indicated by a white arrow); capillary non-perfusion area (indicated by a dashed white arrow). b After intravitreal injection, representative photos of one eye were observed by fundus fluorescein angiography at different time points (1 h, 1 d, 3 d, and 5 d). Blank: blank control group (age-matched rats kept in normoxia with non-intravitreal injection); OIR + NC (negative control group): oxygen-induced retinopathy (OIR) rats with empty-lentivirus intravitreal injection; OIR + ES-LV: OIR rats with endostatin-lentivirus intravitreal injection; OIR + EPCs: OIR rats with EPCs intravitreal injection; OIR + ES-LV-EPCs: OIR rats with endostatin-lentivirus-EPCs intravitreal injection

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