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Fig. 8 | BMC Molecular and Cell Biology

Fig. 8

From: An Endostatin-lentivirus (ES-LV)-EPC gene therapy agent for suppression of neovascularization in oxygen-induced retinopathy rat model

Fig. 8

Photomicrographs of retinal sections labeled with primary antibodies against endostatin, VEGF, and CD31 (immunohistochemistry; magnification × 200). The positive staining is brown (indicated by a black arrow). RNFL+GCL (retinal nerve fiber layer and ganglion cell layer, black words); IPL (inner plexiform layer, black words); INL (inner nuclear layer, white words); OPL (outer plexiform layer, white words); ONL (outer nuclear layer, white words). Scale bar =25 μm. Blank: blank control group (age-matched rats kept in normoxia with non-intravitreal injection); OIR + NC (negative control group): Oxygen-induced retinopathy (OIR) rats with empty-lentivirus intravitreal injection; OIR + ES-LV: OIR rats with endostatin-lentivirus intravitreal injection; OIR + EPCs: OIR rats with EPCs intravitreal injection; OIR + ES-LV-EPCs: OIR rats with endostatin-lentivirus-EPCs intravitreal injection

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