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Fig. 9 | BMC Molecular and Cell Biology

Fig. 9

From: An Endostatin-lentivirus (ES-LV)-EPC gene therapy agent for suppression of neovascularization in oxygen-induced retinopathy rat model

Fig. 9

Endostatin, VEGF, and CD31 expression (IOD/Area, comparison in 5 groups). a Comparison of endostatin expression in the retinas of rats: *P < 0.05 as compared with Blank; #P < 0.05, ##P < 0.01 as compared with OIR + NC. b Comparison of VEGF expression in the retinas of rats: *P < 0.05 as compared with Blank. c Comparison of CD31 expression in the retinas of rats: *P < 0.05 as compared with Blank; #P < 0.05 as compared with OIR + NC. IOD: integral optical density. Blank: blank control group (age-matched rats kept in normoxia with non-intravitreal injection); OIR + NC (negative control group): Oxygen-induced retinopathy (OIR) rats with empty-lentivirus intravitreal injection; OIR + ES-LV: OIR rats with endostatin-lentivirus intravitreal injection; OIR + EPCs: OIR rats with EPCs intravitreal injection; OIR + ES-LV-EPCs: OIR rats with endostatin-lentivirus-EPCs intravitreal injection

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