Fig. 2

Enrichment of PQS in the putative promoters of herpesvirus miRNAs. (a) Violin plot shows the distribution of PQS in native vs randomized sequences. The horizontal black line in the middle of the plot represents the median values for the PQS density. (b) The average PQS densities of the native promoter sequences are significantly higher in the first 200 bp upstream of virus precursor miRNA as compared to that in randomized sequences. Also, the distribution of PQS within the 201–1000 bp window of the native and randomized datasets are comparable to each other. Statistical significance was calculated using Wilcoxon matched-pair signed rank test. P values less than 0.01 were considered significant. NS denotes not significant. The error bars represent the standard deviation within the two datasets