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Fig. 3 | BMC Molecular and Cell Biology

Fig. 3

From: LncRNA LUCAT1/miR-181a-5p axis promotes proliferation and invasion of breast cancer via targeting KLF6 and KLF15

Fig. 3

Downregulation of LUCAT1 reduces cell proliferation, migration and invasion in BC. a Transfection efficiency of si-LUCAT1 was confirmed by qRT-PCR method. b MTT assay: LUCAT1 knockdown in MDA-MB- 231 cells significantly inhibited cell proliferation. c Colony formation assay: colony formation of BC cells was decreased by knockdown of LUCAT1. d Transwell migration assay LUCAT1 knockdown in MDA-MB-231 cells reduced the migration of BC cells. e Transwell invasive assay: LUCAT1 knockdown significantly suppressed cell invasive capacity in BC cells. *p < 0.05

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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