Identification of biomarkers for the accurate and sensitive diagnosis of three bacterial pneumonia pathogens using in silico approaches

Table 5 Physicochemical parameter of the anti-bacterial pneumonia putative AMPs

S/N	Profile	Mass number (Da)	% Hydrophobic	Common amino acid	Net charge	PI	Boman Index (kcal/mol)	Half-life (Hours)
1	BOPAM-AB1	1755.35	52	L	+ 2	10.81	− 1.55	1.1
2	BOPAM-AB2	1789.36	52	L	+ 2	10.81	−1.43	1.1
3	BOPAM-AB3	1909.56	64	L	+ 2	10.81	−2.18	1.1
4	BOPAM-AB4	1849.46	58	L	+ 2	10.81	−1.81	1.1
5	BOPAM-KP2	2370.21	42	NKGV	+ 2	8.70	0.9	30
6	BOPAM-KP3	2478.35	47	NKV	+ 3	8.82	1.18	30
7	BOPAM-KP4	2532.14	28	K	+ 7	10.58	1.5	20
8	BOPAM-KP5	2667.29	39	K	+ 5	9.66	2.3	20
9	BOPAM-KP6	2300.00	38	K	+ 8	10.98	2.28	5.5
10	BOPAM-KP7	2589.16	43	CS	+ 4	8.53	2.0	5.5
11	BOPAM-SP1	5083.36	27	R	+ 6	10.06	3.62	0.8
12	BOPAM-SP2	4903.88	25	G	+ 6	10.00	3.06	1.3
13	BOPAM-SP3	4765.02	45	G	+ 1	6.22	0.47	1.1
14	BOPAM-SP4	4779.05	45	G	+ 1	6.22	0.45	1.1
15	BOPAM-SP5	4779.05	45	G	+ 1	6.22	0.43	1.1
16	BOPAM-SP6	4765.02	45	G	+ 1	6.22	0.47	1.1
17	BOPAM-SP7	4793.07	47	GV	+ 1	6.22	0.36	2.8

LEGEND: S/N Serial number, BOPAM-AB1–5 Putative Anti-Acinetobacter baumannii AMP, BOPAM-SP1–8 Putative Anti-Streptococcus pneumoniae AMP, BOPAM-KP1–2 Putative Anti-Klebsiella pneumoniae AMP

ISSN: 2661-8850