New genotypes of Helicobacter Pylori VacA d-region identified from global strains

Table 3 Frequency of vacA E-, K- and Q- types in CA and NCA patients

VacA	Type	CA (%)	NCA (%)	Total	P-value
‘d’-region	E	14 (12.17)	160 (27.40)	174	0.0007
	K	93 (80.87)	367 (62.84)	460
	Q	8 (6.96)	57 (9.76)	65
s-i-m-c-n-‘E/K’	s1i1m1c1n1E	0 (0)	0 (0)	0	0.0009
combinations	s1i1m1c1n1K	74 (64.35)	293 (50.0)	367
	s2i2m2c2n2E	10 (8.70)	94 (16.04)	104
	s2i2m2c2n2K	0 (0)	2 (0.34)	2
	Others^a	31 (26.96)	197 (33.62)	228

CA Cancer and MALT patients, NCA Atrophic gastritis, intestinal metaplasia, chronic gastritis, functional dyspepsia, gastric ulcer, duodenal ulcer and volunteers. The table also shows the frequencies of E and K types when combined with vacA s, i m, c and n genotypes. Others^a are various combinations that were found other than the ones mentioned in the above table

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