Skip to main content


Fig. 4 | BMC Molecular and Cell Biology

Fig. 4

From: Trophoblast cell differentiation in the bovine placenta: differentially expressed genes between uninucleate trophoblast cells and trophoblast giant cells are involved in the composition and remodeling of the extracellular matrix and O-glycan biosynthesis

Fig. 4

Schematic representation of structural changes in mucin type O-glycans associated with the differentiation of UTCs into TGCs. Green and red arrows indicate up- and downregulated reactions, respectively. The numbers next to the arrows stand for DEG-encoded enzymes catalyzing the addition of the different sugars (GALNTs, N-acetylgalactosaminyltransferases; C1GALT, core 1 beta1,3-galactosyltransferase; GCNTs, beta1,6-N-acetylglucosaminyltransferases; B3GNT6, beta1,3-N-acetylglucosaminyltransferase 6; ST3GAL4, ST3 beta-galactoside alpha2,3-sialyltransferase 4). More details are given in the text. (GalNAc, N-acetylgalactosamine; Gal, galactose; GlcNAc, N-acetylgucosamine; SIA, sialic acid). (Modified from [45])

Back to article page