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Table 2 Annotation clusters (ACs) of DEG-associated GO terms

From: Trophoblast cell differentiation in the bovine placenta: differentially expressed genes between uninucleate trophoblast cells and trophoblast giant cells are involved in the composition and remodeling of the extracellular matrix and O-glycan biosynthesis

AC

Enrichment Score

Topic of clustered GO terms

1

9.47

extracellular exosome; extracellular vesicle

2

7.77

membrane microdomain; membrane raft

3

7.02

lipid metabolic process

4

6.65

(regulation of) cell migration, cell motility

5

6.38

regulation of small GTPase mediated signal transduction

6

5.48

ion binding

7

5.37

positive regulation of cellular protein metabolic process

8

4.98

angiogenesis

9

4.81

(regulation of) signal transduction; cell communication

10

4.36

cell-matrix adhesion

11

4.10

carbohydrate metabolic process

12

4.01

cellular response to chemical stimulus

13

3.76

extracellular matrix

14

3.69

phospholipase activity

15

3.64

GTPase regulator activity

  1. The GO terms and associated DEGs are shown in the Additional file 1: Table S1-E