Trophoblast cell differentiation in the bovine placenta: differentially expressed genes between uninucleate trophoblast cells and trophoblast giant cells are involved in the composition and remodeling of the extracellular matrix and O-glycan biosynthesis

Table 5 DEGs associated with the KEGG pathway “ECM receptor interaction”

DEG	Protein	FC
COL1A1	collagen, type I, alpha 1	−1.75
COL1A2	collagen, type I, alpha 2	−1.75
COL6A1	collagen, type VI, alpha 1	−1.59
LAMA2	laminin, alpha 2	−1.79
LAMA3	laminin, alpha 3	−1.59
LAMB1	laminin, beta 1	−2.50
ITGA1	integrin, alpha 1	1.55
ITGA11	integrin, ITGA11	−1.54
ITGA2	integrin, alpha 2	1.86
ITGA6	integrin, alpha 6	−1.75
ITGB4	integrin, beta 4	−3.13
ITGB5	integrin, beta 5	−2.86
CD36	CD36 molecule (thrombospondin receptor)	1.61
CD44	CD44 molecule	−1.75
COMP	cartilage oligomeric matrix protein	3.20
DAG1	dystroglycan 1 (dystrophin-associated glycoprotein)	1.61
HSPG2	heparan sulfate proteoglycan 2	−1.52
IBSP	integrin-binding sialoprotein	−2.08
RELN	reelin	2.56
SDC4	syndecan 4	−1.67
SPP1	secreted phosphoprotein 1 (osteopontin)	−2,00
SV2B	synaptic vesicle glycoprotein 2B	1.74
THBS1	thrombospondin 1	−1.64
THBS4	thrombospondin 4	−2.33

FC: Fold change; positive and negative values indicate higher and lower transcript abundance in TGCs, respectively

ISSN: 2661-8850