Trophoblast cell differentiation in the bovine placenta: differentially expressed genes between uninucleate trophoblast cells and trophoblast giant cells are involved in the composition and remodeling of the extracellular matrix and O-glycan biosynthesis

Table 6 DEGs encoding ECM-modifying enzymes/proteinases and TIMPs

DEG	Protein	FC
ADAM9	ADAM metallopeptidase domain 9	−1.75
ADAM28	ADAM metallopeptidase domain 28	−1.96
ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	1.67
ADAMTS3	ADAM metallopeptidase with thrombospondin type 1 motif, 3	−1.54
ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9	1.63
ADAMTSL1	ADAMTS-like 1; PUNCTIN	5.23
HPSE	heparanase	3.71
MMP12	matrix metallopeptidase 12	−1.96
MMP13	matrix metallopeptidase 13 (collagenase 3)	−2.04
TIMP1	TIMP metallopeptidase inhibitor 1	−1.56
TIMP2	TIMP metallopeptidase inhibitor 2	1.75
TIMP4	TIMP metallopeptidase inhibitor 4	1.96
TLL2	tolloid-like 2	3.59

FC: Fold change; positive and negative values indicate higher and lower abundance of the transcript in TGCs, respectively

ISSN: 2661-8850