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Fig. 5 | BMC Molecular and Cell Biology

Fig. 5

From: Global transcriptome profile of the developmental principles of in vitro iPSC-to-motor neuron differentiation

Fig. 5

Differential gene expression in key signaling pathways shaping MN differentiation. Gene transcript levels were determined by global RNA-seq analysis of (a) TGFβ, (b) Notch, and (c) Sonic Hedgehog (Shh) pathways and (d) Calcium signaling. Fold change was calculated relative to RNA reads in iPSC (D0). The statistics (average value and standard error) were derived from three independent biological replicas with p < 0.001 determined by R-statistical analysis package

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