Table 4 DEGs identified in KEGG pathway: Axon guidance. Differential expression indicates the average log2-fold change in RNA-Seq transcript levels from three independent experiments at each sampling period: D7 vs D0, D13 vs D7, D18 v D13, and D28 v D18. The p-values were ≤ 0.001. Negative log2-fold change corresponds to gene downregulation and the positive values indicate gene activation
Axon guidance | |||
|---|---|---|---|
Gene ID | Description | Differential expression | Time |
NTNG1 | netrin-G1 | −2.536297436 | D0-D7 |
DCC | deleted in colorectal carcinoma | 2.502983549 | D0-D7 |
NTN1 | netrin 1 | 3.198672486 | D0-D7 |
FYN | tyrosine-protein kinase Fyn | 1.772436052 | D0-D7 |
RGMA | repulsive guidance molecule A | 3.097407276 | D0-D7 |
CXCR4 | C-X-C chemokine receptor type 4 | 4.604478969 | D0-D7 |
CXCL12 | C-X-C motif chemokine 12 | −4.220104913 | D0-D7 |
EPHA3 | Eph receptor A3 | 3.43500774 | D0-D7 |
EPHA4 | Eph receptor A4 | 1.860959561 | D0-D7 |
EPHA7 | EphA7 | 2.088277014 | D0-D7 |
EPHB2 | Eph receptor B2 | 1.873701283 | D0-D7 |
EPHB3 | Eph receptor B3 | 5.416063376 | D0-D7 |
ENAH | Enabled | −0.89497636 | D0-D7 |
SLIT1 | slit 1 | 5.447826267 | D0-D7 |
ROBO2 | roundabout, axon guidance receptor 2 | −2.472827128 | D0-D7 |
NRP1 | neuropilin 1 | 4.117109594 | D0-D7 |
DPYSL5 | dihydropyrimidinase-like 5 | 4.921620042 | D0-D7 |
PTCH1 | patched 1 | 3.517640353 | D0-D7 |
BOC | brother of CDO | 4.811514207 | D0-D7 |
BMP7 | bone morphogenetic protein 7 | 3.232399315 | D0-D7 |
BMPR1B | bone morphogenetic protein receptor type-1B | 1.78373296 | D0-D7 |
DCC | deleted in colorectal carcinoma | 2.626762708 | D7-D13 |
EPHA3 | Eph receptor A3 | 2.836614823 | D7-D13 |
PAK3 | p21-activated kinase 3 | 1.64575883 | D13-D18 |
NTNG1 | netrin-G1 | 2.991377261 | D13-D18 |
EPHA5 | Eph receptor A5 | 3.15278798 | D13-D18 |
SLIT1 | slit 1 | 2.183813571 | D13-D18 |
SLIT2 | slit 2 | 2.342825102 | D13-D18 |
NTNG1 | netrin-G1 | 2.430765649 | D18-D28 |
TRPC5 | transient receptor potential cation channel subfamily C member 5 | 2.464006156 | D18-D28 |
RGS3 | regulator of G-protein signaling 3 | −1.814236062 | D18-D28 |
CXCL12 | C-X-C motif chemokine 12 | 3.751564688 | D18-D28 |
EPHA5 | Eph receptor A5 | 3.524159164 | D18-D28 |
EPHA6 | Eph receptor A6 | 2.585950072 | D18-D28 |
BOC | brother of CDO | −1.858286661 | D18-D28 |
WNT4 | wingless-type MMTV integration site family, member 4 | 2.873234122 | D18-D28 |