Fig. 5

The correlation between the evolutionary age and expression abundance of genes in mammals. a Heatmap shows spearman’s rank correlation coefficients between the evolutionary age (gene age and zinc finger divergence time) and gene expression abundance across early embryonic development, three directions of ESC differentiation in 4 mammals. b Heatmap shows spearman’s rank correlation coefficients between the evolutionary age (gene age and zinc finger divergence time) and gene expression abundance across organs from early organogenesis to adulthood and adult tissues or organs in 7 mammals. Samples with a correlation coefficient over 0.2 are listed in panel (b). For adult tissues or organs datasets of human and mouse, we select a dataset from each of the two species to display in the panel (b). The full raw data of this analysis are shown in Additional file 6. Six types of samples are marked in different colors, including early embryonic development (pink), endoderm differentiation (light blue), mesoderm differentiation (blue), ectoderm differentiation (purple), organs from early organogenesis to adulthood (brown) and adult tissues or organs (black)