Fig. 6

The expressional and functional characteristics of the co-expression modules containing young-zinc-finger-containing KZFPs. a Percentage of young-zinc-finger-containing KZFPs within each co-expression module. The genome-wide percentage of young-zinc-finger-containing KZFPs (0.61%) is indicated with a red circle. Modules exhibiting a significant excess (Bonferroni-corrected P < 0.05) of young-zinc-finger-containing KZFPs are indicated in pink, while nonsignificant modules are shown in gray. The corresponding corrected P-values are marked near the bars. For models in which the percentage of young-zinc-finger-containing KZFPs exceeds the genome-wide percentage, the significantly enriched GO terms are shown. The number of young-zinc-finger-containing KZFPs in each module is shown in brackets. b Boxplots show the TPM values of genes in EM7 during early embryonic development and the ESCs differentiation into endoderm or mesoderm. Samples in each dataset were sorted according to the time point of development or differentiation. Different datasets are separated by red dashed lines. c The expression abundance of young-zinc-finger-containing KZFPs in EM7 during early embryonic development and the ESCs differentiation into endoderm or mesoderm. The zinc finger divergence time of each KZFP is showed below the KZFP name. d Expression correlation as weighted topological overlap (wTO) between genes in EM7. Four young-zinc-finger-containing KZFPs (ZNF267, ZNF845, ZNF93 and ZNF98) are in green. e The wTO between four young-zinc-finger-containing KZFPs (ZNF267, ZNF845, ZNF93 and ZNF98) and other genes in EM7