Fig. 7
From: Avian eggshell biomineralization: an update on its structure, mineralogy and protein tool kit
Schematic representation of the sequential events of mineralization and major matrix proteins at five time points during shell mineralization. The font size is relative to relative protein levels in the eggshell extract. a Proteins having a direct involvement in shell mineralization. Black lettering for proteins with established role in biomineralization. Red lettering for proteins with calcium-binding domains. Purple for proteoglycans and proteoglycan-binding proteins. b Proteins involved in the regulation of proteins directing mineralization. Green lettering for chaperone proteins and blue lettering for proteases and protease inhibitors. Adapted from Marie and coworkers [30, 99]