Fig. 6

TOPFLASH TCF reporter assay. RWPE-1, PC-3, DU-145, and LNCaP cells were transfected with TOP or FOP plasmids and treated with or without 1 mM LiCl for 6 h. Luminescence levels are normalized to non-transfected cells. Data are plotted as the mean ± s.e.m., and four independent experiments were performed. Prostate cancer cells were compared to RWPE-1 cells using Dunnett’s test. **** p < 0.0001