Fig. 3

SEM images of human CF (Baker IV) and murine CF at day 60 and 90. a Human capsules, Baker IV (human capsules were extracted more than 5 to 9 years after implantation) and b murine capsules are shown at days 60 and 90, respectively. Comparable cell infiltration is shown: Both capsules contained coccoid bacteria and a comparable dispersion of blood cells (white blood cells are marked with white triangles), as well as histiocytes (white arrows), that were not found in early stages of CF. c The presence of coccoid bacteria (white arrow) around dispersed silicone particles is shown. d In one murine capsule, a biofilm-fragment of rod-shaped bacteria is shown in the middle of the multidirectional arranged fibers