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Fig. 5 | BMC Molecular and Cell Biology

Fig. 5

From: Complex II subunit SDHD is critical for cell growth and metabolism, which can be partially restored with a synthetic ubiquinone analog

Fig. 5

Glycolysis and ATP synthesis of cell lines. ECAR measured using Agilent Seahorse XFe96 analyzer of 20,000 live cells/well (A), and calculated glycolysis (B) and glycolytic capacity (C) are shown. The mean values were compared between the parent HEK293 and the mutant HEK293ΔSDHD. ATP synthesis of parent and mutant cells measured using Mitochondrial ToxGlo Assay (D) is shown. The measurements are expressed as total luminescence per 3500 or 10,000 cells. Error bars represent the SE of the mean

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