Fig. 2

Genomic landscape surrounding of the snRNA:7SK:94F locus. a Precision Run-On Sequencing (PRO-Seq) analysis of nascent transcripts (GSE131160). PRO-seq signals on both forward and reverse strands are shown, together with RNA abundance measured by sequencing of total RNAs. Forward and reverse reads density are displayed with positive and negative values, respectively. b Evolutionary conservation of the snRNA:7SK:94F locus in arthropods. The comparison is based on 12 Drosophilidae, and 3 insects i.e. the honeybee (A. mellifera), the mosquito (A. gambiae) and the tribolium (T. castaneum) genomes. High sequence conservation is marked by black aligned blocks. Coloured boxes indicate the position of the different structural motifs (M1, M3 and M8) and stems (A and B). Tracks are available at UCSU Genome Browser, assembly version BDGP R5/dm3