Fig. 3

A, Larvae labelled by TUNEL (green) with VASA immunostaining (red) and counterstained with DAPI (blue). PGC of larvae treated with the transcription inhibitor actinomycin-D (1 μg/ml) show impaired migration and undergo apoptosis. B, Representation of apoptotic functions during tail regression. Apoptotic cells emit signals modifying transcription of adjacent cells leading to PGC survival and migration to the trunk