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Table 5 Genes upregulated by the Z-VAD-fmk at mid-tail regression

From: Comparative transcriptomic analysis reveals gene regulation mediated by caspase activity in a chordate organism

KyotoGrail KH gene model

Expression ratio

Identity and/or GO function

References in ascidians/reported functions in animals

KH.C12.516

11,357

neutral ceramidase-like

Kassmer et al. (2015)

migration

KH.C9.170

10,571

protein CNPPD1

x

KH.C2.541

7634

cell cycle control protein 50A

x

KH.C3.623

7551

kinesin-like protein 2

x

KH.C4.189

6713

ribosomal protein CEP52

x

KH.L124.15

5285

vesicular integral-membrane protein VIP36

x

KH.S522.7

5242

TPA: zinc finger protein

x

KH.C14.231

4625

60S ribosomal protein L12

x

KH.S605.3

4398

gamma-crystallin S

x

KH.C9.791

4198

integrin alpha-2-like

migration

KH.C4.73

4127

uncharacterized protein LOC100175287

x

KH.L5.23

4122

uncharacterized protein LOC100179749

x

KH.C1.568

3255

uncharacterized protein LOC100176279

x

KH.S390.2

3227

RNA-binding motif, single-stranded-interacting protein 1

x

KH.C9.660

3187

supervillin-like

migration

KH.L106.13

3179

DENN domain-containing protein 5B-like

x

KH.S534.8

3075

coiled-coil domain-containing protein 178-like

x

KH.L108.23

2846

protein DD3–3

x

KH.C7.614

2824

SLIT and NTRK-like protein 3

x

KH.C2.448

2822

plasminogen

x

KH.C7.297

2732

solute carrier family 22 member 21

x

KH.L37.43

2586

L-threonine ammonia-lyase

x

KH.C11.274

2571

P-selectin-like

Chambon et al., 2007

(ci0100139289)

apoptosis

KH.C11.218

2518

cytospin-A

x

KH.L59.3

2488

uncharacterized protein LOC100175851

x

KH.C10.71

2418

3-phosphoinositide-dependent protein kinase 1

x

KH.C9.715

2397

neurobeachin-like protein 1

x

KH.C3.562

2392

unconventional myosin-X

x

KH.C4.94

2374

lipopolysaccharide-induced tumor necrosis factor-alpha factor

x

KH.S534.2

2333

RB1-inducible coiled-coil protein 1

x

KH.C9.496

2327

uncharacterized protein LOC100183253

x

KH.C1.10

2314

LIM and SH3 protein

Terasaki et al., 2008

KH.C11.93

2252

N-acetyltransferase 6

x

KH.L112.30

2179

transmembrane matrix receptor MUP-4-like

x

KH.C11.567

2162

serine palmitoyltransferase 2

x

KH.L23.11

2094

uncharacterized protein LOC100178692

x

KH.C11.637

2056

putative glutathione-specific gamma-glutamylcyclotransferase 2

x

KH.C7.260

2031

tropomyosin-like protein

Nakayama et al., 2002

migration