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Fig. 4 | BMC Molecular and Cell Biology

Fig. 4

From: Intercellular transfer of mitochondrial DNA carrying metastasis-enhancing pathogenic mutations from high- to low-metastatic tumor cells and stromal cells via extracellular vesicles

Fig. 4

L-EVs and S-EVs isolated from the conditioned medium of P29 and A11 cells. (a) Reflection images of L-EVs and S-EVs. Scale bars: 10 μm. (b) PCR analysis of the presence of mtDNA ND6 gene in L-EVs and S-EVs. (c) Localization of L-EVs and S-EVs added to P29 or A11 cells. P29 or A11 cells were incubated with PKH67-labeled L-EVs or S-EVs for 24 h and observed under a laser confocal microscope. Dashed lines represent the outline of the cells. Scale bars: 20 μm

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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