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Fig. 3 | BMC Molecular and Cell Biology

Fig. 3

From: Uncarboxylated osteocalcin promotes proliferation and metastasis of MDA-MB-231 cells through TGF-β/SMAD3 signaling pathway

Fig. 3

GluOC promotes the expression of MMP2, MMP13 and VEGF in MDA-MB-231 cells. a The expression of MMP2 in MDA-MB-231 cells was analyzed by western blotting and quantified densitometrically with ImageJ software. b Western blot analysis of MMP2 expression in MCF7 cells. c mRNA expression levels of MMP13 and VEGF in MDA-MB-231 and MCF7 cells. The results represent at least three independent experiments, and the data are presented as the mean ± SD (n = 3). *P < 0.05 and **P < 0.01 vs. the control group (con = control). MMP2, matrix metalloproteinase 2; MMP13, matrix metalloproteinase 13; VEGF, vascular endothelial growth factor

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