Fig. 1

MAPKAPK5-AS1 and ZEB1 expressions were up-regulated in HCC, and miR-429 expression was down-regulated. A-C UALCAN database showed the expressions of MAPKAPK5-AS1, miR-429 and ZEB1 in HCC tissues and normal tissues. D-F UALCAN database showed the expressions of MAPKAPK5-AS1, miR-429 and ZEB1 in HCC tissues and normal tissues based on different tumor grades. G-H GEPIA database showed the relationship between the expression of MAPKAPK5-AS1/ ZEB1 and the overall survival of HCC patients. I-K qRT-PCR was used to detect the expressions of MAPKAPK5-AS1, miR-429 and ZEB1 mRNA in HCC tissues and adjacent tissues. L Western blot was used to detect the expression of ZEB1 in HCC tissues and adjacent tissues. M-O qRT-PCR was used to detect the expressions of MAPKAPK5-AS1, miR-429 and ZEB1 mRNA in HCC cell lines (HepG2 and Huh7) and normal human liver cell lines (L02). P Western blot was used to detect the expression of ZEB1 in HCC cell lines (HepG2 and Huh7) and immortalized liver cell line (L02). **P < 0.01; and ***P < 0.001