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Fig.6 | BMC Molecular and Cell Biology

Fig.6

From: Upregulation of CCT3 predicts poor prognosis and promotes cell proliferation via inhibition of ferroptosis and activation of AKT signaling in lung adenocarcinoma

Fig.6

CCT3 stimulates AKT activity. A Ctrl and CCT3 overexpressed H1975 cells, shCtrl, shCCT3#1 and shCCT3#2 H2228 cells were subjected Western blot analysis with indicated antibodies. The blots were cut prior to hybridisation with antibodies during blotting. B Cell viability was the determined by CCK8 assay in Ctrl, CCT3 overexpressed, Ctrl and CCT3 overexpressed H1975 cells that were treated with MK2206 (2 uM) for indicated time. *p < 0.05. **p < 0.01. C Schematic diagram of how CCT3 contributes to LUAD cell growth.

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BMC Molecular and Cell Biology

ISSN: 2661-8850

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