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Fig. 6 | BMC Molecular and Cell Biology

Fig. 6

From: MicroRNA-145-5p modulates Krüppel-like factor 5 and inhibits cell proliferation, migration, and invasion in nasopharyngeal carcinoma

Fig. 6

ML264 suppresses NPC-TW03 and NPC-TW04 cell proliferation, migration, invasion and FAK activity. a Proliferation rates of NPC-TW03 and NPC-TW04 cells 24 to 72 h post-treatment with DMSO or ML264 (2uM). b NPC-TW03 and NPC-TW04 cells were treated with DMSO or ML264 (2uM) and analyzed by wound healing assays. c NPC-TW03 and NPC-TW04 cells were treated with DMSO or ML264 (2uM) and analyzed by invasion assays. d Western blot analysis of KLF5, phospho-FAKTyr397 and FAK levels in NPC-TW03 and NPC-TW04 cells treatment with DMSO or ML264 (2uM) for 24 h, were probes with anti KLF5, phospho-FAKTyr397, FAK and specific antibodies for each compartments corresponding to anti α-tubulin. e Quantification of KLF5 and phospho-FAKTyr397 /FAK expression are the average of three independent experiments, using the Image J software and α-tubulin as a reference. Data are shown as mean ± SD from three independent experiments. *P < 0.05, **P < 0.01, respectively

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