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Fig. 7 | BMC Molecular and Cell Biology

Fig. 7

From: HMGB1 mediates lipopolysaccharide-induced macrophage autophagy and pyroptosis

Fig. 7

Extracellular HMGB1 induces macrophage pyrolysis. Macrophage RAW264.7 were treated with HMGB1 (500 ng/ml) or HMGB1 combined anti-HMGB1 antibodies (1 μg/ml). A, B. The pyroptosis-related protein expressions were detected by western blot. C. The levels of caspase-1 activity were detected. D. The rate of pyroptotic cell was detected by flow cytometry. *P < 0.05, **P < 0.01 versus the control group. #P < 0.05, ##P < 0.01 versus the HMGB1 group

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