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Fig. 1 | BMC Molecular and Cell Biology

Fig. 1

From: RPL11 promotes non-small cell lung cancer cell proliferation by regulating endoplasmic reticulum stress and cell autophagy

Fig. 1

Ribosomal protein 11 (RPL11) is highly expressed in non-small cell lung cancer (NSCLC) cells and promotes cellular proliferation and migration. (a) RPL11 protein level in human bronchial epithelial HBE cells and NSCLC cell lines were detected by western blotting. (b-i) Effects of RPL11 overexpression (b, c, d and e) and siRNA knockdown (f, g, h and i) on NSCLC cell viablity (b and f), colony formation ability (c and g), and migration (d,e, h and i) were evaluated using the CCK8, colony formation, wound healing assays and transwell migration assays. Data are presented as mean ± SD from three independent trials (n = 3). Statistical data of a and f was analyzed using one-way ANOVA, statistical data of b was analyzed using unpaired student’s t-test. *P < 0.05, **P < 0.01, ***P < 0.001

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